September 4, 2000
Minimum free physical memory (RAM) requirement is 50 MB for use with the included HHA series bench at 2.0 mm myocardial cell size (about 32K cells). At least 80 MB of RAM is necessary to create/manipulate HHA series preparations at 1.5 mm; 1 mm HHA series preparations require at least 200 MB of RAM.
If regeneration of Surface Potential Transfer Coefficients is required (e.g. the torso model is modified, the cell size changed, etc.) with a non-zero number of iterations of the procedure of Gelernter and Swihart requested, substantially additional free memory will be required, on the order of 120 megabytes more. Even with zero iterations specified, if Surface Potential Mapping is enabled for any employed polyhedron, approximately additional 40 megabytes is required.
A selection of Benches prebuilt with 2 iterations of the procedure of Gelernter and Swihart is available in the CESLab Bench Library for users requiring maximum simulation accuracy but without sufficient free memory to regenerate Surface Potential Transfer Coefficients on their local computers.
If you experience any apparent CESLab bugs, please send a description of the problem to support@cesinst.com. Any general questions or comments regarding CESLab may also be sent to that address.
This HTML file.
The CESLab application itself.
An HHA series predefined Bench containing a simulated adult human heart with several deactivated pathologies. Cell size is initially 2.0 mm per side, with the Regional Dipole Exclusion Radius set to 3 cm. The CESLab THA adult human inhomogeneous torso model is included, which features a double torso (after Rush and McFee), lungs, and intracavitary polyhedra. Surface Potential Transfer Coefficients have been generated with 2 iterations of the procedure of Gelernter and Swihart, with Surface Potential Mapping enabled for the outer torso polyhedron, lungs, and intracavitary polyhedra.
A directory containing the following HTML documents: CESLab Technical Specifications, User Interface Reference Manual, HHA Bench Technical Specifications (a description of the heart model), THA Torso Model Technical Specifications, and CESLab Glossary of Terminology.
A directory containing various utility scripts, which may be launched in order to perform common alterations of the Current Bench, and run useful sets of trials.
Selecting various Bench Scripts from the "Objects" menu bar entry and running them will demonstrate some of CESLab's more sophisticated simulation capabilities.
Behavior of program is ill-defined after memory allocation failures.
Cells with long action durations do not reactivate neighbors that become repolarized while the first cell is still activated.
If conduction speeds are so low that propagation delays overflow their internal storage variables, conduction is silently suppressed.
Turning off "Is Excitable" does not stop SA Nodes from igniting. User must turn off automaticity as well.
3-D instrument window shading is improperly dependent upon window size.
If both outer and single torso polyhedra are set to "unemployed", an internal error is reported if cardiac cycle simulation is initiated.
Under some conditions, polyhedron generation results in internal errors.
If HDS opened partway through cardiac cycle and trial is continued, a fatal internal error results.
In the HHA series heart models, atrial anatomical obstacles (vessel entry points) are incompletely represented.
Option-clicking in Cell Set Viewer brings up Microscope window at a location on the viewing plane, even if the displayed cell was ahead of the viewing plane. Workaround is to hit the "B" button until the desired area is displayed.
Tissue nodes are always represented by exactly one cell, no matter what radius is specified in the subtissue window.
Changes of dipole sampling interval causes existing data in ECG and HDG windows to be incorrectly rescaled with respect to trial time.
As seen in Polyhedron Editor windows, some polyhedra appear to have cracks in their surfaces. This is an artifact of simplistic drawing algorithms (primitive back-facet culling), and is not associated with actual flaws in the generated polyhedra.
No warning is issued during cell generation if cells from one subtissue are completely overwritten by other subtissues. This occurs only when very large cell sizes are specified.
Editing of "Purkinje CompoundShape" does not render layout of cell set "Purkinje CellSet" out of sync.
To force regeneration of "Purkinje CellSet", open a Cell Set Viewer on the cell set, change the cell size to a different value, hit return, and then change the cell size back to the desired value.
Changes in cell size cause data to be incorrectly scaled in Cell Set Viewers until cell set is resynced.
Background grid in Electrogram windows is sometimes drawn insufficiently wide.
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